Understanding Crohn’s Disease

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Crohn’s disease affects your GI tract, leading to symptoms such as diarrhea and bloody stool. Dietary changes and medications can help you manage some symptoms. However, most people will eventually need surgery.

Crohn’s disease is a type of inflammatory bowel disease (IBD). As many as 780,000 Americans have the condition, according to the Crohn’s & Colitis Foundation of America (CCFA).

More research about Crohn’s disease is necessary. Researchers aren’t sure how it begins, who is most likely to develop it, or how to best manage it. Despite major treatment advances in the last 3 decades, no cure is available yet.

Crohn’s disease most commonly occurs in the small intestine and the colon. It can affect any part of your gastrointestinal (GI) tract, from the mouth to the anus. It can involve some parts of the GI tract and skip other parts.

The range of severity for Crohn’s is mild to debilitating. Symptoms vary and can change over time. In severe cases, the disease can lead to life threatening flares and complications.

Here’s everything you need to know about Crohn’s disease.

Crohn’s symptoms

The symptoms of Crohn’s disease often develop gradually. Certain symptoms may also become worse over time. Although it’s possible, it’s rare for symptoms to develop suddenly and dramatically. The earliest symptoms of Crohn’s disease can include:

  • diarrhea
  • abdominal cramps
  • blood in your stool
  • fever
  • fatigue
  • loss of appetite
  • weight loss
  • feeling as if your bowels aren’t empty after a bowel movement
  • feeling a frequent need for bowel movements

It’s sometimes possible to mistake these symptoms for those of another condition, such as food poisoning, an upset stomach, or an allergy. You should see your doctor if any of these symptoms persist.

The symptoms may become more severe as the disease progresses. More troublesome symptoms may include:

  • a perianal fistula, which causes pain and drainage near your anus
  • ulcers that may occur anywhere from the mouth to the anus
  • inflammation of the joints and skin
  • shortness of breath or decreased ability to exercise due to anemia

Early detection and diagnosis can help you avoid severe complications and allow you to begin treatment early.

What causes Crohn’s disease?

It isn’t clear what causes Crohn’s disease. However, the following factors may influence your chances of developing it:

  • your immune system
  • your genes
  • your environment

Up to 20 percent of people with Crohn’s disease also have a parent, child, or sibling with the disease, according to the CCFA.

According to a 2012 study, certain factors can affect the severity of your symptoms. These include:

  • whether you smoke
  • your age
  • whether or not the rectum is involved
  • length of time you’ve had the disease

People with Crohn’s are also more likely to develop intestinal infections from bacteria, viruses, parasites, and fungi. This can affect the severity of symptoms and create complications.

Crohn’s disease and its treatments can also affect the immune system, making these types of infections worse.

Yeast infections are common in Crohn’s and can affect both the lungs and the intestinal tract. It’s important that these infections are diagnosed and properly treated with antifungal medications to prevent further complications.

Is Crohn’s an autoimmune condition?

An autoimmune condition causes your immune system to mistakenly attack your body, sometimes causing inflammation. Though the immune system could be a potential contributor to inflammation in Crohn’s, it has not yet been classified as an autoimmune condition as the causes are still not fully understood.

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Crohn’s diagnosis

No single test result is enough for your doctor to diagnose Crohn’s disease. They will begin by eliminating other possible causes of your symptoms.

Your doctor may use several types of tests to make a diagnosis:

  • Blood tests can help your doctor look for certain indicators of potential problems, such as anemia and inflammation.
  • A stool test can help your doctor detect blood in your GI tract.
  • Your doctor may request an endoscopy to get a better image of the inside of your upper gastrointestinal tract.
  • Your doctor may request a colonoscopy to examine…

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